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Studies have shown that glucose uptake decreases in advanced CRC, whereas levels of oxidative metabolites such as glutamate and pyruvate increase, indicating a metabolic shift from glycolysis toward a mitochondria-centered hybrid phenotype [6]

Physiol Res

Ezzedine, K

Epigenetic dysregulation has emerged as one of the transcriptional vulnerabilities in human cancer

Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort

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